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Medicine, Health & STEM

作家相片Audrey Fang

The Heart of It All

Hey guys! It's Audrey here, back from our short hiatus (sorry about that!). As a student fascinated by biology and medicine, I feel like I'm always reading about modern surgeries that push the boundaries of medicine (did you see the doctor who wants to perform a full head transplant?). Come with me for a minute back in time, however, to a piece of medical history: the first successful human heart transplant. This milestone, happening on December 3, 1967, by Dr Christiaan Barnard in Cape Town, South Africa, was a unique leap forward in medical science, and opened up new possibilities for transplants, heart disease treatment, and so much more.

Louis Washkansky was a 53-year-old grocer suffering from severe heart failure. His doctors, having exhausted every other option, had to rely on the option of a heart transplant as his last shot. Denise Darvall, who had died in a car accident but was an otherwise young and healthy woman, became the donor in the transplant. Her heart enabled the entire procedure.

Dr Barnard and his team faced a huge challenge. Even though they had mapped things out meticulously, they still had to face the reality of removing Washkansky’s failing heart and replacing it with Darvall’s healthy one - connecting blood vessels 1-to-1 and ensuring the new heart would functioned correctly. A single leak would have spelled disaster. The surgery lasted nine hours (which was pretty wild for the time) and it proved conclusively that a procedure as complex as transplanting a HEART was in fact possible.

Although Washkansky survived the surgery, he faced significant challenges post-operation. The immunosuppressive drugs necessary to prevent his body from rejecting the new heart also made him vulnerable to infections. Despite the best efforts of his medical team, he succumbed to pneumonia 18 days after the transplant. While his survival was brief, the operation was a monumental success, demonstrating that heart transplantation could save lives.

Dr. Barnard's pioneering work set the stage for future advancements. Since then, improvements in surgical techniques, better immunosuppressive medications, and enhanced post-operative care have significantly increased the success rates of heart transplants. Today, thousands of these life-saving procedures are performed annually, giving patients a second chance at life.

For students, this story is more than just a historical milestone. It's about the spirit of bio-innovation, science's determination, and the relentless pursuit of knowledge. It shows how far we've come and what can be achieved when the best medical minds work together to solve complex problems (and isn't that the goal of Inner Workings?).

Maybe someday it will be us contributing to the next big leap in medical history! For now, though, I'm content to just write about it...

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